Year All202620252024202320222021202020192018201720162015 November 21, 2025 Voluntary delisting from Nasdaq takes effect November 11, 2025 Results of AGM October 31, 2025 Quarterly Activities/Appendix 4C Cash Flow Report October 30, 2025 Opthea announces intention to delist from Nasdaq October 27, 2025 Appointment of Company Secretary and CFO October 10, 2025 Notice of Annual General Meeting/Proxy Form October 6, 2025 Opthea Receives A$10.8 million R&D Tax Incentive September 16, 2025 Opthea - Annual General Meeting Date September 15, 2025 2025 Corporate Governance Statement September 15, 2025 Annual Report to shareholders September 5, 2025 S&P DJI Announces September 2025 Quarterly Rebalance September 5, 2025 Application for quotation of securities - OPT